Chirality in drug research

Chirality in drug research edited by Eric Francotte and Wolfgang Lindner. - Weinheim : Wiley-VCH, c2006. - xix, 351 p. : ill. ; 25 cm. - Methods and principles in medicinal chemistry ; v. 33 .

Includes bibliographical references and index.

Chiral drugs from a historical point of view / Joseph Gal -- Stereoselective synthesis of drugs : an industrial perspective / Hans-Jürgen Federsel -- Aspects of chirality in natural products drug discovery / Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt, Ansgar Schuffenhauer -- Biotransformation methods for preparing chiral drugs and drug intermediates / Michael Müller, Marcel Wubbolts -- Resolution of chiral drugs and drug intermediates by crystallisation / Kazuhiko Saigo and Kenichi Sakai -- Isolation and production of optically pure drugs by enantioselective chromatography / Eric Francotte -- Stereoselective chromatographic methods for drug analysis / Norbert M. Maier, Wolfgang Lindner -- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis / Serge Rudaz, Jean-Luc Veuthey -- Powerful chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or ¹H NMR anisotropy methods / Nobuyuki Harada -- Keywords in chirality modeling : molecular modeling of chirality : software and literature research on chirality in modeling, chirality in docking, chiral ligand-receptor interaction and symmetry / Gerd Folkers, Mine Yarim, Pavel Pospisil.

9783527310760 (alk. paper) = Chemistry-reference book collection

2007462582


Chiral drugs.
Drugs--Research.
Drug development.
Chemistry, Pharmaceutical.
Drug Design.
Molecular Conformation.
Stereoisomerism.
Médicaments--Recherche.
Médicaments--Développement.

RS429 / .C488 2006

615.19 F84C

W1 / ME9613H v.33 2006 QV 744 / C5415 2006



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