000			03348nam a22005655i 4500
001			978-3-030-41333-0
003			DE-He213
005			20210602114700.0
007			cr nn 008mamaa
008			200627s2020 gw | s |||| 0|eng d
020			_a9783030413330 _9978-3-030-41333-0
024	7		_a10.1007/978-3-030-41333-0 _2doi
050		4	_aRB155-155.8
050		4	_aQH431
072		7	_aMFN _2bicssc
072		7	_aMED107000 _2bisacsh
072		7	_aMFN _2thema
082	0	4	_a611.01816 _223
100	1		_aNóbrega, Clévio. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut
245	1	2	_aA Handbook of Gene and Cell Therapy _h[electronic resource] / _cby Clévio Nóbrega, Liliana Mendonça, Carlos A. Matos.
250			_a1st ed. 2020.
264		1	_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2020.
300			_aXI, 188 p. 67 illus., 66 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_a1. Gene and Cell therapy overview -- 2. Gene and Cell therapy history -- 3. Delivery systems for gene therapy -- 4. Stem-cells and tissue regeneration theories -- 5. Gene therapy strategies -- 6. Gene and cell therapy applications -- 7. Gene therapy clinical trials -- 8. Research in gene therapy: celllular and animal models -- 9. Future challenges in gene and cell therapy.
520			_aThis is a reference handbook for young researchers exploring gene and cell therapy. Gene therapy could be defined as a set of strategies modifying gene expression or correcting mutant/defective genes through the administration of DNA (or RNA) to cells, in order to treat disease. Important advances like the discovery of RNA interference, the completion of the Human Genome project or the development of induced pluripotent stem cells (iPSc) and the basics of gene therapy are covered. This is a great book for students, teachers, biomedical researchers delving into gene/cell therapy or researchers borrowing skills from this scientific field.
650		0	_aMedical genetics.
650		0	_aGene therapy.
650		0	_aGene expression.
650		0	_aAnimal genetics.
650	1	4	_aGene Function. _0https://scigraph.springernature.com/ontologies/product-market-codes/B12030
650	2	4	_aGene Therapy. _0https://scigraph.springernature.com/ontologies/product-market-codes/B12020
650	2	4	_aGene Expression. _0https://scigraph.springernature.com/ontologies/product-market-codes/B12010
650	2	4	_aAnimal Genetics and Genomics. _0https://scigraph.springernature.com/ontologies/product-market-codes/L32030
700	1		_aMendonça, Liliana. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut
700	1		_aMatos, Carlos A. _eauthor. _4aut _4http://id.loc.gov/vocabulary/relators/aut
710	2		_aSpringerLink (Online service)
773	0		_tSpringer Nature eBook
776	0	8	_iPrinted edition: _z9783030413323
776	0	8	_iPrinted edition: _z9783030413347
776	0	8	_iPrinted edition: _z9783030413354
856	4	0	_uhttps://doi.org/10.1007/978-3-030-41333-0
912			_aZDB-2-SBL
912			_aZDB-2-SXB
999			_c9434 _d9434